The US Centers for Disease Control and Prevention has classified the hantavirus outbreak as a “Level 3” threat and activated its Emergency Operations Centers, sources told ABC News Thursday.

The designation is the lowest level of emergency activation, signifying that the risk to the general public remains low — in line with information given by the World Health Organization earlier Thursday

The CDC is actively monitoring the situation, including by activating the Emergency Operations Centers.

This typically signals that a designated emergency team has been set up to handle hantavirus, the outlet reported. Epidemiologists, scientists, and physicians may be reassigned to monitor and assist with the disease response.

Medics escort a patient evacuated from a cruise ship with suspected hantavirus infection to an ambulance at Schiphol airport.
Medics pictured loading a suspected hantavirus patient onto an ambulance at Amsterdam’s Schiphol airport in the Netherlands.AP

Many small natural disasters in the US tend to involve Level 3 responses under the CDC’s Emergency Management Program.

The CDC said in a statement on Wednesday that are “closely monitoring the situation with U.S. travelers onboard the M/V Hondius cruise ship with confirmed hantavirus.”

“The Department of State is leading a coordinated, whole-of-government response, including direct contact with passengers, diplomatic coordination, and engagement with domestic and international health authorities,” the statement added.

President Trump said he has been briefed on the hantavirus outbreak on the Dutch-flagged ship MV Hondius, which is en route to the Canary Islands and expected to arrive Saturday.

“It should be fine. We hope,” he told reporters while speaking about the outbreak. “It’s very much – we hope – under control.”

He confirmed that a “full report” will be issued Friday – but stopped short of providing the exact details on what it might feature.

Trump also tried to reassure Americans when asked if they should be worried about the outbreak.

“I hope not, I mean, I hope not,” he said. “We’ll do the best we can.”

State agencies are monitoring American passengers who were on board the ship and have since returned home.

Microscope image of liver tissue affected by Hantavirus Pulmonary Syndrome.
A microscopic image of liver tissue affected by Hantavirus Pulmonary Syndrome.US Centers for Disease Control and Prevention (CDC)/AFP via Getty Images
The passengers did not know that they had been exposed to the virus when they left the boat at Saint Helena on April 24.

Texas said the two residents have agreed to monitor their temperature daily for possible infection — but they are not currently showing infection.

The two Georgia residents are in good health, showing no signs of infection and following recommendations from the Centers for Disease Control and Prevention, the Georgia Department of Public Health said.

The Arizona passenger was not experiencing symptoms either, according to the state’s health services department.

Drone view of the cruise ship MV Hondius departing Praia.
The MV Hondius has departed Cape Verde and is now en route to the Canary Islands.REUTERS
The Virginia resident was “currently in good health” and being monitored, the Virginia Department of Health said.

Six Americans were among the 30 passengers who disembarked during the ship’s stop in Saint Helena, the vessel’s operator, Oceanwide Expeditions, revealed Thursday.

Hantavirus reached Europe earlier this week, with a man, who had left the boat, turning himself into a Zurich, Switzerland, hospital after exhibiting symptoms.

The European Centre for Disease Prevention and Control has also activated its response regarding the Andes hantavirus outbreak, which carries a mortality rate of 40%.

Health workers in protective gear evacuate patients from the MV Hondius cruise ship into an ambulance at a port in Praia, Cape Verde.
Health workers, who are pictured wearing protective gear, seen loading a patient into an ambulance in Cape Verde.AP
Officials confirmed Wednesday that an EU Health Force Task official had been deployed to the cruise ship.

Similarly to its American counterparts, the ECDC has said the risk to the population is very low.

Three suspected hantavirus patients were evacuated from the MV Hondius while it was in West African waters, off the coast of Cape Verde, and are receiving treatment.

Map illustrating the timeline of a hantavirus outbreak on a ship traveling from Argentina to the Canary Islands.
Three hantavirus deaths have been reported so far during the outbreak.NY Post Design
Former British cop Martin Anstee, who now works as an expedition guide on the liner, was airlifted to an Amsterdam, Netherlands, hospital.

A 41-year-old Dutch national and a 65-year-old German national were removed from the ship alongside Anstee on Wednesday.

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Eight suspected hantavirus cases have been reported, including three deaths, the World Health Organization confirmed.

But, Dr Tedros Adhanom Ghebreyesus, the WHO Director-General, said, “It’s possible more cases may be reported.”

A British man, 69, is being treated in a South African hospital but the UK’s Health Security Agency announced Friday an additional suspected case of the virus on the South Atlantic island of Tristan da Cunha.

The MV Hondius stopped briefly on the archipelago in mid-April.